Ibogamine
From Wikipedia, the free encyclopedia
 |
|
 |
|
| Clinical data | |
|---|---|
| ATC code | none |
| Identifiers | |
|
|
| CAS Number | 481-87-8  |
| PubChem (CID) | 100217 |
| ChemSpider | 90568  |
| ChEBI | CHEBI:5853 |
| Chemical and physical data | |
| Formula | C19H24N2 |
| Molar mass | 280.41 g/mol |
|
|
| (what is this?) (verify) |
|
Ibogamine is an alkaloid found in Tabernanthe iboga.[1][2]
Basic research related to how addiction affects the brain has used this chemical.[3]
Ibogamine persistently reduced the self-administration of cocaine and morphine in rats.[4]
See also[edit]
References[edit]
- ^ Bartlett, M. F.; Dickel, D. F.; Taylor, W. I. (1958). "The Alkaloids of Tabernanthe iboga. Part IV.1 The Structures of Ibogamine, Ibogaine, Tabernanthine and Voacangine - Journal of the American Chemical Society (ACS Publications)". Journal of the American Chemical Society. 80 (1): 126–136. doi:10.1021/ja01534a036.
- ^ Kuehne, Martin E.; Reider, Paul J. (1985). "A synthesis of ibogamine - The Journal of Organic Chemistry (ACS Publications)". The Journal of Organic Chemistry. 50 (9): 1464–1467. doi:10.1021/jo00209a020.
- ^ Levi MS, Borne RF (October 2002). "A review of chemical agents in the pharmacotherapy of addiction". Curr. Med. Chem. 9 (20): 1807–18. doi:10.2174/0929867023368980. PMID 12369879.
- ^ Glick SD, Kuehne ME, Raucci J, Wilson TE, Larson D, Keller RW Jr, Carlson JN (September 1994). "Effects of iboga alkaloids on morphine and cocaine self-administration in rats: relationship to tremorigenic effects and to effects on dopamine release in nucleus accumbens and striatum.". Brain Res. 657 (1-2): 14–22. doi:10.1016/0006-8993(94)90948-2. PMID 7820611.
 |
This drug article relating to the nervous system is a stub. You can help Wikipedia by expanding it. |
