RH-34

RH-34
Clinical data
Routes of; administration	?
ATC code	none;
Legal status
Legal status	In general: uncontrolled;
Identifiers
	IUPAC name 3-[2-(2-methoxybenzylamino)ethyl]-1H-quinazoline-2,4-dione;
CAS Number	1028307-48-3 ;
PubChem CID	10041987;
ChemSpider	8217551 ;
UNII	A31AED225O;
Chemical and physical data
Formula	C18H19N3O3
Molar mass	325.361 g/mol
3D model (Jmol)	Interactive image;
	SMILES O=c1[nH]c2ccccc2c(=O)n1CCNCc3ccccc3OC ;
	InChI InChI=1S/C18H19N3O3/c1-24-16-9-5-2-6-13(16)12-19-10-11-21-17(22)14-7-3-4-8-15(14)20-18(21)23/h2-9,19H,10-12H2,1H3,(H,20,23) ; Key:NUAJBITWGGTZCM-UHFFFAOYSA-N ;
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RH-34 is a compound which acts as a potent and selective partial agonist for the 5-HT_2A serotonin receptor subtype. It was derived by structural modification of the selective 5-HT_2A antagonist ketanserin, with the 4-(p-fluorobenzoyl)piperidine moiety replaced by the N-(2-methoxybenzyl) pharmacophore found in such potent 5-HT_2A agonists as NBOMe-2C-B and NBOMe-2C-I. This alteration was found to retain 5-HT_2A affinity and selectivity, but reversed activity from an antagonist to a moderate efficacy partial agonist.^[1]^[2]^[3]

Legal status[edit]

RH-34 is a controlled substance in Hungary.^[4]

Clinical data

Routes of administration	?
ATC code	none
Legal status
Legal status	In general: uncontrolled
Identifiers
IUPAC name 3-[2-(2-methoxybenzylamino)ethyl]-1H-quinazoline-2,4-dione
CAS Number	1028307-48-3^N
PubChem CID	10041987
ChemSpider	8217551^N
UNII	A31AED225O
Chemical and physical data
Formula	C₁₈H₁₉N₃O₃
Molar mass	325.361 g/mol
3D model (Jmol)	Interactive image
SMILES O=c1[nH]c2ccccc2c(=O)n1CCNCc3ccccc3OC
InChI InChI=1S/C18H19N3O3/c1-24-16-9-5-2-6-13(16)12-19-10-11-21-17(22)14-7-3-4-8-15(14)20-18(21)23/h2-9,19H,10-12H2,1H3,(H,20,23)^N Key:NUAJBITWGGTZCM-UHFFFAOYSA-N^N
^NY (what is this?) (verify)