Fluorolintane

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Fluorolintane
Fluorolintane structure.png
Identifiers
Chemical and physical data
Formula C18H20FN
Molar mass 269.36 g·mol−1
3D model (Jmol) Interactive image

Fluorolintane (also known as 2-FPPP) is a dissociative anesthetic drug that has been sold online as a designer drug.[1][2]

Fluorolintane and related diarylethylamines are antagonists of the NMDA receptor[3] and have been studied in vitro as potential treatments for neurotoxic injury,[4] depression[5] and as sympathomimetic.[6]

See also[edit]

References[edit]

  1. ^ Jason Wallach; Pierce V. Kavanagh; Gavin McLaughlin; Noreen Morris; John D. Power; Simon P. Elliott; Marion S. Mercier; David Lodge; Hamilton Morris; Nicola M. Dempster; Simon D. Brandt (May 2014). "Preparation and characterization of the 'research chemical' diphenidine, its pyrrolidine analogue, and their 2,2-diphenylethyl isomers". Drug Testing and Analysis. 7 (5): 358–367. doi:10.1002/dta.1689. PMID 25044512. 
  2. ^ "Analytical Report - Fluorolintane" (PDF). Nacionalni forenzični laboratorij (NFL). January 2016. 
  3. ^ Michael L. Berger; Anna Schweifer; Patrick Rebernik; Friedrich Hammerschmidt (May 2009). "NMDA receptor affinities of 1,2-diphenylethylamine and 1-(1,2-diphenylethyl)piperidine enantiomers and of related compounds". Bioorganic & Medicinal Chemistry. 17 (1): 3456–3462. doi:10.1016/j.bmc.2009.03.025. PMID 19345586. 
  4. ^ Nancy M. Gray; Brian K. Cheng. "Patent EP 0346791 B1 - 1,2-diarylethylamines for treatment of neurotoxic injury". Retrieved 17 June 2015. 
  5. ^ Brooke D Aspergren; Richard V Heinzelman (1963). "Patent US 3083139 A - Therapeutic 1-(1, 2-diphenylethyl) pyrrolidine for the management of depression". Retrieved 22 June 2015. 
  6. ^ R. V. Heinzelman; B. D. Aspergren (July 1953). "Compounds Containing the Pyrrolidine Ring. Analogs of Sympathomimetic Amines". Journal of the American Chemical Society. 75 (14): 3409–3413. doi:10.1021/ja01110a033. 


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