2,2,2-Trichloroethanol
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Names | |||
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IUPAC name
2,2,2-Trichloroethanol
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3D model (Jmol)
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ECHA InfoCard | 100.003.701 | ||
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Properties | |||
C2H3Cl3O | |||
Molar mass | 149.40 g/mol | ||
Density | 1.55 g/cm3 | ||
Melting point | 17.8 °C (64.0 °F; 290.9 K) | ||
Boiling point | 151 °C (304 °F; 424 K) | ||
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references | |||
2,2,2-Trichloroethanol is an organic compound related to ethanol, except the hydrogen atoms at position 2 are replaced with chlorine atoms. In humans, its pharmacological effects are similar to those of its prodrugs, chloral hydrate and chlorobutanol. It has, historically, been used as a sedative hypnotic.[1] The hypnotic drug triclofos (2,2,2-trichloroethyl phosphate) is metabolized in vivo to 2,2,2-trichloroethanol. Chronic exposure may result in kidney and liver damage.[2]
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References[edit]
- ^ The Merck Index, 13th Edition.
- ^ S. Budavari; M. O'Neil; Ann Smith; P. Heckelman; J. Obenchain (15 March 1996). The Merck Index (12th print ed.). Taylor & Francis. ISBN 978-0-911910-12-4.
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See also: GABAergics
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