6-CAT

6-CAT
Clinical data
Routes of; administration	Oral
Legal status
Legal status	In general: uncontrolled;
Identifiers
	IUPAC name 6-Chloro-1,2,3,4-tetrahydronaphtalen-2-amine;
PubChem CID	16244336;
ChemSpider	11269876 ;
Chemical and physical data
3D model (Jmol)	Interactive image;
	SMILES C1CC2=C(CC1N)C=CC(=C2)Cl ;
	InChI InChI=1S/C10H12ClN/c11-9-3-1-8-6-10(12)4-2-7(8)5-9/h1,3,5,10H,2,4,6,12H2 ; Key:CJRJTCMSQLEPFQ-UHFFFAOYSA-N ;
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6-Chloro-2-aminotetralin (6-CAT) is a drug which acts as a selective serotonin releasing agent (SSRA) and is a putative entactogen in humans.^[1]^[2] It is a rigid analogue of para-chloroamphetamine (PCA).^[1]

According to Nichols et al.,^[3] 6-CAT is a non-neurotoxic analog of PCA.

References[edit]

^ ^a ^b Fuller RW; Perry KW; Baker JC; Molloy BB (November 1974). "6-Chloro-2-aminotetralin, a rigid Conformational analog of 4-chloroamphetamine: pharmacologic properties of it and related compounds in rats". Archives Internationales de Pharmacodynamie et de Thérapie. 212 (1): 141–53. PMID 4455127.
^ Fuller, RW; Wong, DT; Snoddy, HD; Bymaster, FP (1977). "Comparison of the effects of 6-chloro-2-aminotetralin and of ORG 6582, a related chloroamphetamine analog, on brain serotonin metabolism in rats". Biochem. Pharmacol. 26 (1): 1,333–1,337.
^ Johnson, M. P.; Frescas, S. P.; Oberlender, R.; Nichols, D. E. (1991). "Synthesis and pharmacological examination of 1-(3-methoxy-4-methylphenyl)-2-aminopropane and 5-methoxy-6-methyl-2-aminoindan: Similarities to 3,4-(methylenedioxy)methamphetamine (MDMA)". Journal of Medicinal Chemistry. 34 (5): 1662–1668. doi:10.1021/jm00109a020. PMID 1674539.

v t e Empathogens/entactogens (category)

Phenylalkyl- amines (other than cathinones)	Unfused benzene ring: 4-CAB 4-FA 4-FMA 4-MTA 4,4'-DMAR Ariadne Metaescaline MMA PMA PMEA PMMA Benzodioxine: EDMA Benzodioxoles: Phenethylamine: { Lophophine } Amphetamines: { 2-Methyl-MDA 2,3-MDA 3,4-MDA 5-Methyl-MDA 6-Methyl-MDA DiFMDA DMMDA DMMDA-2 EIDA MDEA MDMA MDMOH MDOH MMDA MMDA-2 MMDMA } 1-Phenylbutan-2-amines: { BDB EBDB MBDB } Phentermines: { MDMP MDPH } Benzofurans and dihidrobenzofurans: 5-APB 5-APDB 5-EAPB 5-MAPB 5-MAPDB 5-MBPB 6-APB 6-APDB 6-EAPB 6-MAPB 6-MAPDB Indanes: 5-APDI 5-MAPDI Indole: 6-API Naphtalenes: Methamnetamine Naphthylaminopropane Tetralin: 6-APT

Cyclized phenyl- alkylamines	Aminoindanes: 5-IAI AMMI ETAI MDAI MDMAI MMAI NM-2-AI TAI Aminotetralins: 6-CAT MDAT MDMAT

Cathinones	3-MMC 4-EMC Brephedrone Butylone Ethylone Eutylone Flephedrone Mephedrone Methedrone Methylone Pentylone

Tryptamines	4-Methyl-αET αET αMT

Chemical classes	Substituted amphetamine Sub. benzofuran Sub. cathinone Sub. MDPEA Sub. PEA Sub. tryptamine

Clinical data

Routes of administration	Oral
Legal status
Legal status	In general: uncontrolled
Identifiers
IUPAC name 6-Chloro-1,2,3,4-tetrahydronaphtalen-2-amine
PubChem CID	16244336
ChemSpider	11269876^Y
Chemical and physical data
3D model (Jmol)	Interactive image
SMILES C1CC2=C(CC1N)C=CC(=C2)Cl
InChI InChI=1S/C10H12ClN/c11-9-3-1-8-6-10(12)4-2-7(8)5-9/h1,3,5,10H,2,4,6,12H2^Y Key:CJRJTCMSQLEPFQ-UHFFFAOYSA-N^Y
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