LAMP3

LAMP3
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 4AKM
Identifiers
Aliases	LAMP3, CD208, DC LAMP, DC-LAMP, DCLAMP, LAMP, LAMP-3, TSC403, lysosomal-associated membrane protein 3, lysosomal associated membrane protein 3
External IDs	MGI: 2441659 HomoloGene: 8670 GeneCards: LAMP3
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	27074	239739
Ensembl	ENSG00000078081	ENSMUSG00000041247
UniProt	Q9UQV4	Q7TST5
RefSeq (mRNA)	NM_014398	NM_177356
RefSeq (protein)	NP_055213	NP_796330
Location (UCSC)	Chr 3: 183.12 – 183.16 Mb	Chr 16: 19.65 – 19.71 Mb
PubMed search
Wikidata
View/Edit Human View/Edit Mouse

Lysosome-associated membrane glycoprotein 3 (LAMP3, Lamp3) is a protein that in humans is encoded by the LAMP3 gene. It is one of the lysosome-associated membrane glycoproteins.

Further reading

• de Saint-Vis B, Vincent J, Vandenabeele S, et al. (1998). "A novel lysosome-associated membrane glycoprotein, DC-LAMP, induced upon DC maturation, is transiently expressed in MHC class II compartment.". Immunity. 9 (3): 325–36. PMID 9768752. doi:10.1016/S1074-7613(00)80615-9. 
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. PMC 139241 . PMID 12477932. doi:10.1073/pnas.242603899. 
• Akasaki K, Nakamura N, Tsukui N, et al. (2004). "Human dendritic cell lysosome-associated membrane protein expressed in lung type II pneumocytes.". Arch. Biochem. Biophys. 425 (2): 147–57. PMID 15111122. doi:10.1016/j.abb.2004.02.042. 
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. PMC 528928 . PMID 15489334. doi:10.1101/gr.2596504. 
• Kanao H, Enomoto T, Kimura T, et al. (2005). "Overexpression of LAMP3/TSC403/DC-LAMP promotes metastasis in uterine cervical cancer.". Cancer Res. 65 (19): 8640–5. PMID 16204031. doi:10.1158/0008-5472.CAN-04-4112. 
• Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes.". Genome Res. 16 (1): 55–65. PMC 1356129 . PMID 16344560. doi:10.1101/gr.4039406. 
• Arruda LB, Sim D, Chikhlikar PR, et al. (2006). "Dendritic cell-lysosomal-associated membrane protein (LAMP) and LAMP-1-HIV-1 gag chimeras have distinct cellular trafficking pathways and prime T and B cell responses to a diverse repertoire of epitopes.". J. Immunol. 177 (4): 2265–75. PMID 16887987. doi:10.4049/jimmunol.177.4.2265. 
• Zhu LC, Yim J, Chiriboga L, et al. (2007). "DC-LAMP stains pulmonary adenocarcinoma with bronchiolar Clara cell differentiation.". Hum. Pathol. 38 (2): 260–8. PMID 17056097. doi:10.1016/j.humpath.2006.07.018. 
• Elliott B, Scolyer RA, Suciu S, et al. (2007). "Long-term protective effect of mature DC-LAMP+ dendritic cell accumulation in sentinel lymph nodes containing micrometastatic melanoma.". Clin. Cancer Res. 13 (13): 3825–30. PMID 17606713. doi:10.1158/1078-0432.CCR-07-0358. 

This article incorporates text from the United States National Library of Medicine, which is in the public domain.