Estradiol butyrate benzoate
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Intramuscular |
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Systematic (IUPAC) name: [(8R,9S,13S,14S,17S)-17-butanoyloxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-3-yl] benzoate
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| CAS Number | 63042-18-2 |
| PubChem (CID) | 67081 |
| ChemSpider | 60431 |
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| Formula | C29H34O4 |
| Molar mass | 446.57786 g/mol |
| 3D model (Jmol) | Interactive image |
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Estradiol butyrate benzoate, or estradiol 3-benzoate 17β-n-butyrate, also known as estra-1,3,5(10)-triene-3,17β-diol 3-benzoate 17β-n-butyrate, is a semisynthetic, steroidal estrogen and an estrogen ester – specifically, the 3-benzoate 17β-n-butyrate diester of estradiol – which was never marketed.[1][2] Under the tentative brand name Unimens, estradiol butyrate benzoate was studied in combination with the progestogen algestone acetophenide (dihydroxyprogesterone acetophenide) as a once-monthly combined injectable contraceptive (at doses of 10 mg and 150 mg, respectively).[1][2][3]
See also[edit]
References[edit]
- ^ a b Toppozada M (1977). "The clinical use of monthly injectable contraceptive preparations". Obstet Gynecol Surv. 32 (6): 335–47. PMID 865726.
- ^ a b Mokhtar K. Toppozada (1983), Monthly Injectable Contraceptives (PDF)
- ^ Elsayed Saad Eldin Hafez (1980). Human reproduction: conception and contraception. Harper and Row. ISBN 978-0-06-141066-6.
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