Drupanol
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| Formula | C18H24O |
| Molar mass | 256.387 g/mol |
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Drupanol is a naturally occurring phenol that has been isolated from the seeds of Psoralea drupaceae.[1][2][3] Although drupanol is sometimes said to be the same compound as bakuchiol, the two compounds are in fact distinct; they have the same molecular formula and weight but different chemical structures and hence are structural isomers.[1][2] Drupanol has been found to possess androgenic and anabolic activity and hence is a phytoandrogen.[4] In contrast to drupanol, bakuchiol has been found to possess antiandrogen activity.[5]
References[edit]
- ^ a b J. Elks (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. p. 120,473. ISBN 978-1-4757-2085-3.
- ^ a b Li, Cong-Cong; Wang, Teng-Long; Zhang, Zhong-Qun; Yang, Wen-Qiang; Wang, Yue-Fei; Chai, Xin; Wang, Chun-Hua; Li, Zheng (2016). "Phytochemical and Pharmacological Studies on the Genus Psoralea: A Mini Review". Evidence-Based Complementary and Alternative Medicine. 2016: 1–17. ISSN 1741-427X. doi:10.1155/2016/8108643.
- ^ Golovina, L. A.; Nikonov, G. K. (1973). "The structure of drupanol — A new phenol from Psoralea drupaceae". Chemistry of Natural Compounds. 9 (1): 7–9. ISSN 0009-3130. doi:10.1007/BF00580876.
- ^ Sasha W. Eisenman; David E. Zaurov; Lena Struwe (14 September 2012). Medicinal Plants of Central Asia: Uzbekistan and Kyrgyzstan. Springer Science & Business Media. pp. 205–. ISBN 978-1-4614-3912-7.
- ^ Miao, L., Ma, S. W., Fan, G. W., Wang, H., Wang, Y. F., & Chai, L. J. (2013). Bakuchiol inhibits the androgen induced-proliferation of prostate cancer cell line LNCaP through suppression of AR transcription activity. Tianjin Journal of Traditional Chinese Medicine, 5, 012.
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