Potassium canrenoate
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Clinical data | |
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AHFS/Drugs.com | International Drug Names |
Routes of administration |
Intravenous |
ATC code | |
Pharmacokinetic data | |
Metabolism | Hepatic |
Excretion | Renal and fecal |
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Synonyms | SC-14266 |
CAS Number | |
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ChEMBL | |
ECHA InfoCard | 100.016.868 |
Chemical and physical data | |
Formula | C22H29KO4 |
Molar mass | 396.5616 g/mol |
3D model (Jmol) | |
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Potassium canrenoate (INN, JAN) or canrenoate potassium (USAN) (brand names Venactone, Soldactone), also known as aldadiene kalium,[1] the potassium salt of canrenoic acid, is an aldosterone antagonist of the spirolactone group.[2] Like spironolactone, it is a prodrug, which is metabolized to canrenone in the body. Potassium canrenoate is not licensed in the UK, but may sometimes be prescribed off-licence to treat oedema. It is given intravenously.
See also[edit]
References[edit]
- ^ Hans Selye (17 April 2013). Hormones and Resistance: Part 1 and. Springer Science & Business Media. pp. 186–. ISBN 978-3-642-65192-2.
- ^ R.A. Hill; H.L.J. Makin; D.N. Kirk; G.M. Murphy (23 May 1991). Dictionary of Steroids. CRC Press. pp. 656–. ISBN 978-0-412-27060-4.
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20,22-Desmolase (P450scc) |
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17α-Hydroxylase, 17,20-Lyase |
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3β-HSD | |
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21-Hydroxylase | |
11β-Hydroxylase |
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18-Hydroxylase |
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5α-Reductase |
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Aromatase |
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27-Hydroxylase | |
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