Ethylmorphine
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Clinical data | |
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AHFS/Drugs.com | International Drug Names |
ATC code | R05DA01 (WHO) S01XA06 (WHO) |
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CAS Number | 76-58-4 |
PubChem (CID) | 5359271 |
DrugBank | DB01466 |
ChemSpider | 4514250 |
UNII | RWO67D87EU |
ECHA InfoCard | 100.000.883 |
Chemical and physical data | |
Formula | C19H23NO3 |
Molar mass | 313.391 g/mol |
3D model (Jmol) | Interactive image |
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Ethylmorphine (also known as codethyline, dionine, and ethyl morphine) is an opioid analgesic and antitussive.[1][2][3][4][5][6]
See also[edit]
References[edit]
- ^ Xu, Bang Qian; Aasmundstad, Tor A.; Lillekjendlie, Bjern; Bjørneboe, Anders; Christophersen, Asbjørg S.; Mørland, Jørg (April 1997). "Effects of Ethanol on Ethylmorphine Metabolism in Isolated Rat Hepatocytes: Characterization by Means of a Multicompartmental Model". Pharmacology & Toxicology. 80 (4): 171–181. doi:10.1111/j.1600-0773.1997.tb00392.x. ISSN 1600-0773. PMID 9140136.
- ^ Jonasson, B.; Jonasson, U.; Holmgren, P.; Saldeen, T. (August 1999). "Fatal poisonings where ethylmorphine from antitussive medications contributed to death". International Journal of Legal Medicine. 112 (5): 299–302. doi:10.1007/s004140050253. ISSN 1437-1596. PMID 10460420.
- ^ Popa, Cornelia; Beck, Olof; Brodin, Kerstin (March–April 1998). "Morphine Formation from Ethylmorphine: Implications for Drugs-of-Abuse Testing in Urine". Journal of Analytical Toxicology. 22 (2): 142–147. doi:10.1093/jat/22.2.142. ISSN 1945-2403. PMID 9547411.
- ^ Amacher, David E; Schomaker, Shelli J (31 January 1998). "Ethylmorphine N-demethylase activity as a marker for cytochrome P450 CYP3A activity in rat hepatic microsomes". Toxicology Letters. 94 (2): 115–125. doi:10.1016/S0378-4274(97)00108-2. PMID 9574808.
- ^ Aasmundstad, Ta; Xu, Bq; Johansson, I.; Ripel, A.; Bjorneboe, A.; Christophersen, As; Bodd, E.; Morland, J. (June 1995). "Biotransformation and pharmacokinetics of ethylmorphine after a single oral dose.". British Journal of Clinical Pharmacology. 39 (6): 611–620. doi:10.1111/j.1365-2125.1995.tb05720.x. ISSN 1365-2125. PMC 1365072. PMID 7654478.
- ^ Liu, Z; Mortimer, O; Smith, Ca; Wolf, Cr; Rane, A (January 1995). "Evidence for a role of cytochrome P450 2D6 and 3A4 in ethylmorphine metabolism.". British Journal of Clinical Pharmacology. 39 (1): 77–80. doi:10.1111/j.1365-2125.1995.tb04413.x. ISSN 1365-2125. PMC 1364985. PMID 7756104.
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