Thiorphan
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Formula | C12H15NO3S |
Molar mass | 253.32 g/mol |
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Chirality | Racemic mixture |
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Thiorphan is the active metabolite of the antidiarrheal racecadotril (acetorphan).[1] It prevents the degradation of endogenous enkephalins by acting as an enkephalinase inhibitor.[1]
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References[edit]
- ^ a b Spillantini MG, Geppetti P, Fanciullacci M, Michelacci S, Lecomte JM, Sicuteri F (June 1986). "In vivo 'enkephalinase' inhibition by acetorphan in human plasma and CSF". European Journal of Pharmacology. 125 (1): 147–50. PMID 3015640. doi:10.1016/0014-2999(86)90094-4.
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