Nitecapone
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Systematic (IUPAC) name | |
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3-(3,4-dihydroxy-5-nitrobenzylidene)-2,4-pentanedione
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Identifiers | |
CAS Number | 116313-94-1 |
ATC code | None |
PubChem | CID 5464105 |
ChemSpider | 4576539 |
Chemical data | |
Formula | C12H11NO6 |
Molar mass | 265.219 g/mol |
3D model (Jmol) | Interactive image |
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Nitecapone (INN; OR-462) is a drug which acts as a selective inhibitor of the enzyme catechol O-methyl transferase (COMT).[1][2] It was patented as an antiparkinsonian agent but was never marketed.[1]
See also[edit]
References[edit]
- ^ a b F.. Macdonald (1997). Dictionary of Pharmacological Agents. CRC Press. p. 1635. ISBN 978-0-412-46630-4. Retrieved 20 May 2012.
- ^ Nissinen E, Lindén IB, Schultz E, Kaakkola S, Männistö PT, Pohto P (August 1988). "Inhibition of catechol-O-methyltransferase activity by two novel disubstituted catechols in the rat". European Journal of Pharmacology. 153 (2-3): 263–9. doi:10.1016/0014-2999(88)90614-0. PMID 3181288.
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