FZD2

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FZD2
Identifiers
Aliases FZD2, Fz2, fz-2, fzE2, hFz2, frizzled class receptor 2
External IDs MGI: 1888513 HomoloGene: 20377 GeneCards: FZD2
RNA expression pattern
PBB GE FZD2 210220 at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001466

NM_020510

RefSeq (protein)

NP_001457

NP_065256.1
NP_065256

Location (UCSC) Chr 17: 44.56 – 44.56 Mb Chr 11: 102.6 – 102.61 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Frizzled-2 is a protein that in humans is encoded by the FZD2 gene.[3][4][5]

Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The expression of the FZD2 gene appears to be developmentally regulated, with high levels of expression in fetal kidney and lung and in adult colon and ovary.[5]

See also[edit]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Zhao Z, Lee CC, Baldini A, Caskey CT (Nov 1995). "A human homologue of the Drosophila polarity gene frizzled has been identified and mapped to 17q21.1". Genomics. 27 (2): 370–3. doi:10.1006/geno.1995.1060. PMID 7558010. 
  4. ^ Sagara N, Toda G, Hirai M, Terada M, Katoh M (Dec 1998). "Molecular cloning, differential expression, and chromosomal localization of human frizzled-1, frizzled-2, and frizzled-7". Biochem Biophys Res Commun. 252 (1): 117–22. doi:10.1006/bbrc.1998.9607. PMID 9813155. 
  5. ^ a b "Entrez Gene: FZD2 frizzled homolog 2 (Drosophila)". 

External links[edit]

  • "Frizzled Receptors: FZD2". IUPHAR Database of Receptors and Ion Channels. International Union of Basic and Clinical Pharmacology. 

Further reading[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.