- published: 26 Jun 2015
- views: 16835
In molecular biology, CD4 (cluster of differentiation 4) is a glycoprotein found on the surface of immune cells such as T helper cells, monocytes, macrophages, and dendritic cells. It was discovered in the late 1970s and was originally known as leu-3 and T4 (after the OKT4 monoclonal antibody that reacted with it) before being named CD4 in 1984. In humans, the CD4 protein is encoded by the CD4 gene.
CD4+ T helper cells are white blood cells that are an essential part of the human immune system. They are often referred to as CD4 cells, T-helper cells or T4 cells. They are called helper cells because one of their main roles is to send signals to other types of immune cells, including CD8 killer cells, which then destroy the infectious particle. If CD4 cells become depleted, for example in untreated HIV infection, or following immune suppression prior to a transplant, the body is left vulnerable to a wide range of infections that it would otherwise have been able to fight.
Like many cell surface receptors/markers, CD4 is a member of the immunoglobulin superfamily.
I can't know what you feel inside.
But your face can't hide your foolish pride.
Keep in mind all you left behind
Was in chains that bind: is that a sign?
I can't read what you keep inside your mind,
Protecting what I find within your walls.
Things I feel that I know just can't be real.
Trick and try to steal my life away.
Cold deception goes both ways.
Watch yourself or you'll get bathed.
In the darkness that is light.
As your spirit dies tonight.
I'll tell you something- I know I must be strong.
For your giving me something- That I know is wrong.
I can't know what you feel inside,
But your face can't hide your foolish pride.
Keep in mind all you left behind
Was in chains that bind: is that a sign?
Your intentions become clear.
All deceptions disappear.
The inception of your plan.
Marks the end of modern man.
I'll tell you something- I know I must be strong.