MDK may refer to:
MDK is a third-person shooter video game series. MDK is a series of three games (two separate games and a re-make of the second) which place the player in the control of Kurt Hectic, a janitor on Doctor Hawkins's ship, the "Jim Dandy". In each game, the Earth is under attack by "Streamriders", aliens who ride energy streams to the earth's surface in order to take over the planet. The Streamriders' purpose is to strip the earth of its minerals and resources. In the first game, Kurt is the only playable character, but in the second game, you gain the opportunity to play as him, Doctor Hawkins, and his genetically-engineered pet dog, Bones (often called "Max").
The game tells the story of its protagonist, Kurt Hectic, and his attempts to rescue Earth from an alien invasion of gigantic strip mining city-vehicles named 'Minecrawlers' that are not only removing all of Earth's natural resources but are also flattening any people and cities that get in their way. The game combines action with a sense of humour.
Midkine (MK or MDK) also known as neurite growth-promoting factor 2 (NEGF2) is a protein that in humans is encoded by the MDK gene.
Midkine is a basic heparin-binding growth factor of low molecular weight, and forms a family with pleiotrophin (NEGF1, 46% homologous with MK). It is a nonglycosylated protein, composed of two domains held by disulfide bridges. It is a developmentally important retinoic acid-responsive gene product strongly induced during mid-gestation, hence the name midkine. Restricted mainly to certain tissues in the normal adult, it is strongly induced during oncogenesis, inflammation and tissue repair.
MK is pleiotropic, capable of exerting activities such as cell proliferation, cell migration, angiogenesis and fibrinolysis. A molecular complex containing receptor-type tyrosine phosphatase zeta (PTPζ), low density lipoprotein receptor-related protein (LRP1), anaplastic leukemia kinase (ALK) and syndecans is considered to be its receptor.
MK appears to enhance the angiogenic and proliferative activities of cancer cells. The expression of MK (mRNA and protein expression) has been found to be elevated in multiple cancer types, such as neuroblastoma, glioblastoma, Wilms’ tumors, thyroid papillary carcinomas, colorectal, liver, ovary, bladder, breast, lung, esophageal, stomach, and prostate cancers. Serum MK in normal individuals is usually less than 0.5-0.6 ng/ml, whereas patients with these malignancies have much higher levels than this. In some cases, these elevated levels of MK also indicate a poorer prognosis of the disease, such as in neuroblastoma, gliablastoma, and bladder carcinomas. In neuroblastoma, for example, the levels of MK are elevated about three times the level in Stage 4 of the cancer (one of the final stages) than they are in Stage 1.
A remix is a piece of media which has been altered from its original state by adding, removing, and/or changing pieces of the item. A song, piece of artwork, book, video, or photograph can all be remixes. The only characteristic of a remix is that it appropriates and changes other materials to create something new.
Most commonly, remixes are associated with music and songs. Songs are remixed for a variety of reasons:
Remix is a Candan Erçetin album. There are remixes of "Neden" in this album. There is also a song named "Yazık Oldu" which is a song from Pjer Žalica's movie Fuse.
"Remix (I Like The)" is a song by American pop group New Kids on the Block from their sixth studio album, 10. The song was released as the album's lead single on January 28, 2013. "Remix (I Like The)" was written by Lars Halvor Jensen, Johannes Jørgensen, and Lemar, and it was produced by Deekay. The song features Donnie Wahlberg and Joey McIntyre on lead vocals.
"Remix (I Like The)" did not enter the Billboard Hot 100 in the United States, becoming their first lead single to fail charting since "Be My Girl" (1986). Instead, the song peaked at number 38 on the Adult Pop Songs chart.
PopCrush gave the song 3.5 stars out of five. In her review Jessica Sager wrote, "The song sounds like an adult contemporary answer to The Wanted mixed with Bruno Mars‘ ‘Locked Out of Heaven.’ It has a danceable beat like many of the British bad boys’ tracks, but is stripped down and raw enough to pass for Mars’ latest radio smash as well." Carl Williott of Idolator commended the song's chorus, but criticized its "liberal use of Auto-Tune" and compared Donnie Wahlberg's vocals to Chad Kroeger.
Hood are an English indie rock band from Leeds, formed in 1991. The band consists of brothers Chris and Richard Adams, and friends (including, at times, Craig Tattersall and Andrew Johnson of The Remote Viewer, and Nicola Hodgkinson of Empress).
Hood's first releases were very limited vinyl singles on various small independent record labels.
In 1994, record labels Fluff and Slumberland Records released Hood's first full length album, Cabled Linear Traction. Slumberland also released 1996's Silent '88, and the following year Happy Go Lucky Records released Structured Disasters, a compilation of tracks from singles. All featured a large number of short tracks (many of less than a minute), a mixture of indie rock, noise experiments reminiscent of Sonic Youth or Pavement, and an increasing interest in electronics.
In 1997, Domino Records signed Hood and released the single "Useless". Produced by Matt Elliott (better known as the Third Eye Foundation), it was a far more straightforward and tuneful song than any they had released so far. Elliott toured with the band, and produced the albums Rustic Houses, Forlorn Valleys and The Cycle of Days and Seasons. Like the single, these abandoned the short songs and instrumental snippets for longer pieces, with a pastoral sound similar to Bark Psychosis or Talk Talk. The band continued to release singles for other labels; "The Weight", for 555 Recordings, was a return to the older style with eight tracks on a 7" disc.