Amedalin
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Clinical data | |
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ATC code | None |
Identifiers | |
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CAS Number | 22136-26-1 22232-73-1 (HCl) |
PubChem (CID) | 31075 |
ChemSpider | 28832 |
UNII | 2OWK6X9N16 |
KEGG | D02891 |
ChEMBL | CHEMBL2110769 |
Chemical and physical data | |
Formula | C19H22N2O |
Molar mass | 294.3925 g/mol |
3D model (Jmol) | Interactive image |
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Amedalin (UK-3540-1) is an antidepressant which was synthesized in the early 1970s, but was never marketed.[1][2] It is a selective norepinephrine reuptake inhibitor, with no significant effects on the reuptake of serotonin and dopamine, and no antihistamine or anticholinergic properties.[2][3]
See also[edit]
References[edit]
- ^ David J. Triggle (1997). Dictionary of pharmacological agents. London: Chapman & Hall. ISBN 0-412-46630-9.
- ^ a b Canas-Rodriquez A, Leeming PR (1972). "N-Phenyl-2-indolinones and N-phenylindolines - New class of antidepressant agents". Journal of Medicinal Chemistry. 15 (7): 762–770. doi:10.1021/jm00277a017.
- ^ Koe BK (December 1976). "Molecular geometry of inhibitors of the uptake of catecholamines and serotonin in synaptosomal preparations of rat brain". Journal of Pharmacology and Experimental Therapeutics. 199 (3): 649–661.
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