Azapride

Azapride
Clinical data
ATC code	none
Identifiers
	IUPAC name 4-Azido-5-chloro-2-methoxy-N-[1-(phenylmethyl)piperidin-4-yl]benzamide;
CAS Number	92990-90-4
PubChem (CID)	3036441
ChemSpider	2300456
Chemical and physical data
Formula	C20H22ClN5O2
Molar mass	399.87
3D model (Jmol)	Interactive image
	SMILES Clc1cc(c(OC)cc1/N=[N+]=[N-])C(=O)NC3CCN(Cc2ccccc2)CC3 ;
	InChI InChI=1S/C20H22ClN5O2/c1-28-19-12-18(24-25-22)17(21)11-16(19)20(27)23-15-7-9-26(10-8-15)13-14-5-3-2-4-6-14/h2-6,11-12,15H,7-10,13H2,1H3,(H,23,27) ; Key:CKKHIIXHAWWTNP-UHFFFAOYSA-N ;
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Azapride is the azide derivative of the dopamine antagonist clebopride synthesized in order to label dopamine receptors.^[1]^[2] It is an irreversible dopamine antagonist.^[3]

References[edit]

^ Niznik HB, Guan JH, Neumeyer JL, Seeman P. (1985) 'A photoaffinity ligand for dopamine D2 receptors: azidoclebopride.', Mol Pharmacol.
^ Wouters W, Van Dun J, Laduron PM.(1984),'Photoaffinity labelling of dopamine receptors. Synthesis and binding characteristics of azapride.', Eur J Biochem.
^ European Journal of Biochemistry 1984, 145(2), p.273

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