Pentolinium

Pentolinium
Identifiers
	IUPAC name 1-Methyl-1-[5-(1-methylpyrrolidin-1-ium-1-yl)pentyl]pyrrolidin-1-ium;
CAS Number	144-44-5; 52-62-0 (tartrate salt)
PubChem (CID)	5850
DrugBank	DB01090
ChemSpider	5641
UNII	ULL76WPU5X
ChEMBL	CHEMBL1271
Chemical and physical data
Formula	C15H32N2
Molar mass	240.43 g/mol
	InChI InChI=1S/C15H32N2/c1-16(12-6-7-13-16)10-4-3-5-11-17(2)14-8-9-15-17/h3-15H2,1-2H3/q+2 ; Key:XSBSKEQEUFOSDD-UHFFFAOYSA-N ;

Pentolinium is a ganglionic blocking agent which acts as a nicotinic acetylcholine receptor antagonist. It can be used as an antihypertensive drug during surgery or to control hypertensive crises. It works by binding to the acetylcholine receptor of adrenergic nerves and thereby inhibiting the release of noradrenaline and adrenaline. Blocking this receptor leads to smooth muscle relaxation and vasodilatation. Pentolinium can be given orally, injected intramuscularly or administered intravenously.^{[citation needed]}

Overview[edit]

It's molecular formula is (C₁₅H₃₂N₂)²⁺.^[1]

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Identifiers

IUPAC name 1-Methyl-1-[5-(1-methylpyrrolidin-1-ium-1-yl)pentyl]pyrrolidin-1-ium
CAS Number	144-44-5 52-62-0 (tartrate salt)
PubChem (CID)	5850
DrugBank	DB01090
ChemSpider	5641
UNII	ULL76WPU5X
ChEMBL	CHEMBL1271
Chemical and physical data
Formula	C₁₅H₃₂N₂
Molar mass	240.43 g/mol
InChI InChI=1S/C15H32N2/c1-16(12-6-7-13-16)10-4-3-5-11-17(2)14-8-9-15-17/h3-15H2,1-2H3/q+2 Key:XSBSKEQEUFOSDD-UHFFFAOYSA-N