Exaprolol
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Names | |
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IUPAC name
1-(2-Cyclohexylphenoxy)-3-(propan-2-ylamino)propan-2-ol
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Other names
Esprolol
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Identifiers | |
55837-19-9 | |
3D model (Jmol) | Interactive image |
ChemSpider | 58934 |
PubChem | 65485 |
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Properties | |
C18H29NO2 | |
Molar mass | 291.44 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references | |
Exaprolol is a beta-adrenoceptor antagonist.[1]
Synthesis[edit]
![](http://web.archive.org./web/20170206202413im_/https://upload.wikimedia.org/wikipedia/commons/thumb/c/cc/Exaprolol_synthesis.svg/500px-Exaprolol_synthesis.svg.png)
Exaprolol synthesis:[2]
References[edit]
- ^ Van Waarde, A; Doorduin, J; De Jong, JR; Dierckx, RA; Elsinga, PH (2008). "Synthesis and preliminary evaluation of (S)-11C-exaprolol, a novel beta-adrenoceptor ligand for PET". Neurochemistry international. 52 (4–5): 729–33. doi:10.1016/j.neuint.2007.09.009. PMID 17961850.
- ^ Carissimi, M; Gentili, P; Grumelli, E; Milla, E; Picciola, G; Ravenna, F (1976). "Basic ethers of cyclohexylphenols with beta-blocking activity: Synthesis and pharmacological study of exaprolol". Arzneimittel-Forschung. 26 (4): 506–16. PMID 8056.
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