Fenspiride
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| Clinical data | |
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| Trade names | Eurespal, Pneumorel |
| AHFS/Drugs.com | International Drug Names |
| Routes of administration |
Oral |
| ATC code | R03BX01 (WHO) R03DX03 (WHO) |
| Legal status | |
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| Pharmacokinetic data | |
| Bioavailability | 90%[1] |
| Biological half-life | 14–16 hours |
| Excretion | Urine (90%), feces (~10%) |
| Identifiers | |
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| CAS Number | 5053-06-5  |
| PubChem (CID) | 68626 |
| DrugBank | DB08979  |
| ChemSpider | 3227 |
| UNII | S983QC7HKM |
| KEGG | D07949 |
| ChEMBL | CHEMBL576127 |
| ECHA InfoCard | 100.023.411 |
| Chemical and physical data | |
| Formula | C15H20N2O2 |
| Molar mass | 260.331 g/mol |
| 3D model (Jmol) | Interactive image |
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Fenspiride (INN, brand names Eurespal, Pneumorel and others) is an oxazolidinone spiro compound used as a drug in the treatment of certain respiratory diseases.[2] The pharmacotherapeutic classification is antitussives. In Russia it is approved for the treatment of acute and chronic inflammatory diseases of ENT organs (ear, nose, throat) and the respiratory tract (like rhinopharyngitis, laryngitis, tracheobronchitis, otitis and sinusitis), as well as for maintenance treatment of asthma.[3]
References[edit]
- ^ Montes, B; Catalan, M; Roces, A; Jeanniot, JP; Honorato, JM (1993). "Single dose pharmacokinetics of fenspiride hydrochloride: phase I clinical trial.". European journal of clinical pharmacology. 45 (2): 169–72. doi:10.1007/bf00315501. PMID 7901024.
- ^ Płusa T, Nawacka D (Dec 1998). "Efficacy and tolerance of fenspiride in adult patients with acute respiratory tract infections". Pol Merkur Lekarski. 5 (30): 368–71. PMID 10101527.
- ^ "Эреспал® (Eurespal®) Prescribing Information. VIDAL Drug Compendium" (in Russian). Retrieved 6 February 2014.
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