Glafenine

Glafenine
Clinical data
ATC code	N02BG03 (WHO)
Identifiers
	IUPAC name 2,3-Dihydroxypropyl 2-[(7-chloro-4-quinolinyl)amino]benzoate;
CAS Number	3820-67-5
PubChem (CID)	3474
ChemSpider	3355
ChEBI	CHEBI:31653
ChEMBL	CHEMBL146095
ECHA InfoCard	100.021.197
Chemical and physical data
Formula	C19H17ClN2O4
Molar mass	372.802 g/mol
3D model (Jmol)	Interactive image
Melting point	169 to 170 °C (336 to 338 °F)
	SMILES O=C(OCC(O)CO)c1ccccc1Nc2c3ccc(Cl)cc3ncc2 ;
	InChI InChI=1S/C19H17ClN2O4/c20-12-5-6-14-17(7-8-21-18(14)9-12)22-16-4-2-1-3-15(16)19(25)26-11-13(24)10-23/h1-9,13,23-24H,10-11H2,(H,21,22) ; Key:GWOFUCIGLDBNKM-UHFFFAOYSA-N ;

Glafenine is a non-steroidal anti-inflammatory drug (NSAID). Use of glafenine is limited due to the risk of anaphylaxis and acute kidney failure.^[1]^[2]

References[edit]

^ "Withdrawal of glafenine". The Lancet. 339 (8789): 357. 1992. doi:10.1016/0140-6736(92)91670-4.
^ Kleinknecht, D; Landais, P; Goldfarb, B (1986). "Analgesic and non-steroidal anti-inflammatory drug-associated acute renal failure: A prospective collaborative study". Clinical nephrology. 25 (6): 275–81. PMID 2873910.

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