Zolantidine
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Clinical data | |
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ATC code | None |
Identifiers | |
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CAS Number | 104076-38-2 |
PubChem (CID) | 91769 |
ChemSpider | 82866 |
UNII | M1108XAY01 ![]() |
ChEMBL | CHEMBL419296 |
Chemical and physical data | |
Formula | C22H27N3OS |
Molar mass | 381.5 g/mol |
3D model (Jmol) | Interactive image |
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Zolantidine is a brain-penetrating selective histamine H2 receptor (HRH2) antagonist developed by Smith, Kline & French, with the research code of SK&F 95282. It is a benzthiazole derivative with a 30-fold higher potency for H2 receptors than other peripheral and central receptors.[1]
References[edit]
- ^ Calcutt, CR; Ganellin, CR; Griffiths, R; Leigh, BK; Maguire, JP; Mitchell, RC; Mylek, ME; Parsons, ME; Smith, IR; Young, RC (January 1988). "Zolantidine (SK&F 95282) is a Potent Selective Brain-penetrating Histamine H2-receptor Antagonist". British Journal of Pharmacology. 93 (1): 69–78. doi:10.1111/j.1476-5381.1988.tb11406.x. PMC 1853786
. PMID 2894879.
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