Toloxatone

Toloxatone
Clinical data
Routes of; administration	Oral
ATC code	N06AG03 (WHO);
Legal status
Legal status	In general: uncontrolled;
Identifiers
	IUPAC name 5-(hydroxymethyl)-3-m-tolyloxazolidin-2-one;
CAS Number	29218-27-7 ;
PubChem CID	34521;
ChemSpider	31769 ;
UNII	5T206015T5;
KEGG	D02559 ;
ChEMBL	CHEMBL18116 ;
ECHA InfoCard	100.045.006
Chemical and physical data
Formula	C11H13NO3
Molar mass	207.226 g/mol
3D model (Jmol)	Interactive image;
	SMILES O=C2OC(CO)CN2c1cccc(c1)C ;
	InChI InChI=1S/C11H13NO3/c1-8-3-2-4-9(5-8)12-6-10(7-13)15-11(12)14/h2-5,10,13H,6-7H2,1H3 ; Key:MXUNKHLAEDCYJL-UHFFFAOYSA-N ;
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Toloxatone (Humoryl) is an antidepressant launched in 1984 in France for the treatment of depression. It acts as a selective reversible inhibitor of MAO-A (RIMA).^[1]

References[edit]

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v t e Anxiolytics (N05B)

5-HT_1A agonists	Buspirone Tandospirone

GABA_AR PAMs	Benzodiazepines: Adinazolam Alprazolam Bromazepam Camazepam Chlordiazepoxide Clobazam Clonazepam Clorazepate Clotiazepam Cloxazolam Diazepam^# Ethyl loflazepate Etizolam Fludiazepam Halazepam Ketazolam Lorazepam^# Medazepam Nordazepam Oxazepam Pinazepam Prazepam Others: Alpidem^‡ Barbiturates Carbamates Chlormezanone^‡ Ethanol Etifoxine; Herbs: Kava Skullcap Valerian

α₂δ VDCC blockers	Gabapentin Gabapentin enacarbil Phenibut Pregabalin

Antidepressants	SSRIs SNRIs SARIs TCAs TeCAs MAOIs; Others: Agomelatine Bupropion Vilazodone Vortioxetine

Sympatholytics	Beta blockers (e.g., propranolol) Clonidine Dexmedetomidine Guanfacine Prazosin

Others	Benzoctamine Cannabidiol Cycloserine Fabomotizole Hydroxyzine Kanna Lavender Lorpiprazole Mebicar Mepiprazole Nicotine Opipramol Oxaflozane^‡ Phenaglycodol Phenibut Picamilon Selank Tiagabine Tofisopam Validolum

Clinical data

Routes of administration	Oral
ATC code	N06AG03 (WHO)
Legal status
Legal status	In general: uncontrolled
Identifiers
IUPAC name 5-(hydroxymethyl)-3-m-tolyloxazolidin-2-one
CAS Number	29218-27-7^N
PubChem CID	34521
ChemSpider	31769^Y
UNII	5T206015T5
KEGG	D02559^Y
ChEMBL	CHEMBL18116^Y
ECHA InfoCard	100.045.006
Chemical and physical data
Formula	C₁₁H₁₃NO₃
Molar mass	207.226 g/mol
3D model (Jmol)	Interactive image
SMILES O=C2OC(CO)CN2c1cccc(c1)C
InChI InChI=1S/C11H13NO3/c1-8-3-2-4-9(5-8)12-6-10(7-13)15-11(12)14/h2-5,10,13H,6-7H2,1H3^Y Key:MXUNKHLAEDCYJL-UHFFFAOYSA-N^Y
^NY (what is this?) (verify)