Pyrrobutamine

Pyrrobutamine
Clinical data
ATC code	R06AX08 (WHO)
Identifiers
	IUPAC name 1-[(2E)-4-(4-chlorophenyl)-3-phenylbut-2-en-1-yl]pyrrolidine;
CAS Number	91-82-7
PubChem (CID)	5284614
ChemSpider	4447659
UNII	VE6KP18S8X
ChEMBL	CHEMBL1697849
ECHA InfoCard	100.001.911
Chemical and physical data
Formula	C20H22ClN
Molar mass	311.848 g/mol
3D model (Jmol)	Interactive image
	SMILES C1CCN(C1)C/C=C(\CC2=CC=C(C=C2)Cl)/C3=CC=CC=C3 ;
	InChI InChI=1S/C20H22ClN/c21-20-10-8-17(9-11-20)16-19(18-6-2-1-3-7-18)12-15-22-13-4-5-14-22/h1-3,6-12H,4-5,13-16H2/b19-12+ ; Key:WDYYVNNRTDZKAZ-XDHOZWIPSA-N ;
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Pyrrobutamine is an antihistamine and anticholinergic.^[1]

References[edit]

^ Mothersill, M. H.; Mills, J.; Lee, H. M.; Anderson, R. C.; Harris, P. N. (1953). "Chemical and pharmacological characteristics of the antihistaminic compound, pyrrobutamine". Annals of allergy. 11 (6): 754–757. PMID 13114796.

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v t e Antihistamines (R06)

Aminoalkyl ethers	Bromazine (bromodiphenhydramine) Carbinoxamine Clemastine Chlorphenoxamine Diphenylpyraline Diphenhydramine Doxylamine Orphenadrine Phenyltoloxamine

Substituted alkylamines	Brompheniramine Chlorphenamine Dexbrompheniramine (+pseudoephedrine) Dexchlorpheniramine (+betamethasone) Dimetindene Pheniramine Talastine

Substituted ethylenediamines	Chloropyramine Histapyrrodine Mepyramine Methapyrilene Tripelennamine (pyribenzamine)

Phenothiazine derivatives	Alimemazine Fenethazine Hydroxyethylpromethazine Isothipendyl Mequitazine Methdilazine Oxomemazine Promethazine

Piperazine derivatives	Buclizine Cetirizine Levocetirizine Chlorcyclizine Cinnarizine Cyclizine Hydroxyzine Meclizine Oxatomide

Others for systemic use	Antazoline Azanator Azatadine Bamipine Cyproheptadine Deptropine Ebastine Emedastine Epinastine Ketotifen Latrepirdine Mebhydrolin Mizolastine Olopatadine Phenindamine Pimethixene Pyrrobutamine Quifenadine Rupatadine Triprolidine selective (Acrivastine Astemizole Azelastine Bilastine Desloratadine Fexofenadine Loratadine Terfenadine)

For topical use	Bamipine Chloropyramine Chlorphenoxamine Clemastine Dimetindene Diphenhydramine Isothipendyl Mepyramine Promethazine Thenalidine