3-(p-Fluorobenzoyloxy)tropane
tropane.png) |
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| Routes of administration |
insufflated |
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| CAS Number | 172883-97-5  |
| PubChem (CID) | 5147770 |
| ChemSpider | 4321292  |
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| Formula | C15H18FNO2 |
| Molar mass | 263.307 g/mol |
| 3D model (Jmol) | Interactive image |
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3β-(p-Fluorobenzoyloxy)tropane, (8-Methyl-8-azabicyclo[3.2.1]oct-3-yl 4-fluorobenzoic acid ester, 4-fluorotropacocaine, 3-Pseudotropyl-4-fluorobenzoate, 3-pseudotropyl-4-fluorobenzoate, pFBT) is a tropane derivative drug which acts as a local anaesthetic, having around 30% the stimulant potency of cocaine but around the same potency as a local anaesthetic.[citation needed] It has been investigated as a potential radiolabelled agent for studying receptor binding,[1] but was not adopted for this application. The main application for fluorotropacocaine, however, has been as a designer drug analogue of cocaine, first detected by the EMCDDA in 2008,[2][3] and subsequently sold as an ingredient of various "bath salt" powder products, usually mixed in combination with other stimulant drugs such as caffeine, dimethocaine, desoxypipradrol or substituted cathinone derivatives.[4][5]
See also[edit]
References[edit]
- ^ Ali M. Emran. New Trends in Radiopharmaceutical Synthesis, Quality Assurance, and Regulatory Control. Springer, 1991. p84. ISBN 0-306-44035-0
- ^ Wohlfarth, A.; Weinmann, W. (2010). "Bioanalysis of new designer drugs". Bioanalysis. 2 (5): 965–979. doi:10.4155/bio.10.32. PMID 21083227.
- ^ Kavanagh P, Angelov D, O'Brien J, Fox J, O'Donnell C, Christie R, Power JD, McDermott SD. The syntheses and characterization 3β-(4-fluorobenzoyloxy)tropane (fluorotropacocaine) and its 3α isomer. Drug Testing and Analysis. 2011 Nov 18. doi:10.1002/dta.362 PMID 22102564
- ^ An overview of new psychoactive substances and the outlets supplying them
- ^ Reitzel LA, Dalsgaard PW, Müller IB, Cornett C. Identification of ten new designer drugs by GC-MS, UPLC-QTOF-MS, and NMR as part of a police investigation of a Danish Internet company. Drug Testing and Analysis. 2011 Nov 18. doi:10.1002/dta.358 PMID 22102551
