Decoglurant
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ATC code | none |
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CAS Number | 911115-16-7 |
PubChem (CID) | 71533696 |
ChemSpider | 32695160 |
Chemical and physical data | |
Formula | C21H11F6N5 |
Molar mass | 447.336 g/mol |
3D model (Jmol) | Interactive image |
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Decoglurant (INN) (code name RG1578, RO4995819) is a negative allosteric modulator of the mGlu2 and mGlu3 receptors which was under development by Roche for the adjunctive treatment of major depressive disorder.[1][2] Decoglurant progressed as far as phase II clinical trials[1][2] but was ultimately discontinued from further development due to disappointing efficacy results.[3][4]
See also[edit]
References[edit]
- ^ a b "Roche - Pipeline". 2014. Retrieved 2014-08-01.
- ^ a b "Roche Group Development Pipeline" (PDF). 2014. Retrieved 2014-08-01.
- ^ "Roche - Pipeline" (PDF). 2015. Retrieved 2015-05-14.
- ^ Janna Lawrence (March 2015). "The Secret Life of ketamine". The Pharmaceutical Journal.
External links[edit]
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