Azatadine
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| Trade names | Optimine |
| AHFS/Drugs.com | Micromedex Detailed Consumer Information |
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| ATC code | R06AX09 (WHO) |
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| CAS Number | 3964-81-6  |
| PubChem (CID) | 19861 |
| IUPHAR/BPS | 7119 |
| DrugBank | DB00719 |
| ChemSpider | 18709 |
| UNII | 94Z39NID6C |
| KEGG | D07482 |
| ChEBI | CHEBI:2946 |
| ChEMBL | CHEMBL946 |
| Chemical and physical data | |
| Formula | C20H22N2 |
| Molar mass | 290.402 g/mol |
| 3D model (Jmol) | Interactive image |
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Azatadine (Optimine) is a first-generation antihistamine and anticholinergic that was launched Schering-Plough in 1973.[1][2]
It was patented in 1967.[3] It has been succeeded by other antihistamines[4]:53 and marketing approvals have been widely withdrawn.[5][6][7][8]:290[9]
See also[edit]
References[edit]
- ^ Katelaris, C. (1990). "Comparative effects of loratadine and azatadine in the treatment of seasonal allergic rhinitis". Asian Pacific Journal of Allergy and Immunology. 8 (2): 103–107. PMID 1982614.
- ^ Small, P.; Barrett, D.; Biskin, N. (1990). "Effects of azatadine, terfenadine, and astemizole on allergen-induced nasal provocation". Annals of allergy. 64 (2 Pt 1): 129–131. PMID 1968324.
- ^ Azatadine, Villani, F. J.; Caldwell, W. U.S. Patent 3,326,924 (1967).
- ^ Horak F. Antialergic and Vasoactive Drugs for Allergic Rhinitis. Chapter 4 in Allergy Frontiers:Therapy and Prevention. Volume 5 of Allergy Frontiers. Eds Pawankar R et al Springer Science & Business Media, 2010 ISBN 9784431993629
- ^ Drugs.com Drugs.com listing for Azatadine Page accessed July 3, 2015
- ^ Federal Register 2005 Food and Drug Administration Docket No.2005N-0058: Hospira, Inc. et al.; Withdrawal of Approval of 76 New Drug Applications and 60 Abbreviated New Drug Applications 70 FR 10651
- ^ Federal Register 2007 Food and Drug Administration Docket No. 2004P-0262: Withdrawal of Approval of 128 Suitability Petitions 72 FR 8184
- ^ Department of Economic and Social Affairs of the United Nations Secretariat Consolidated List of Products Whose Consumption and/or Sale Have Been Banned, Withdrawn, Severely Restricted or not Approved by Governments Twelfth Issue: Pharmaceuticals United Nations – New York, 2005
- ^ FDA OGD Suitability Tracking Report (Sorted by Drug Name) Page accessed July 3, 2015
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