Unoprostone

Unoprostone

Clinical data
Trade names	Rescula
AHFS/Drugs.com	Micromedex Detailed Consumer Information
Pregnancy category	US: C (Risk not ruled out)
Routes of administration	Topical (eye drops)
ATC code	S01EE02 (WHO)
Legal status
Legal status	US: Discontinued
Pharmacokinetic data
Biological half-life	14 min
Excretion	Renal
Identifiers
IUPAC name (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-(3-oxodecyl) cyclopentyl]hept-5-enoic acid
CAS Number	120373-36-6 Y 120373-24-2 (isopropyl ester)
PubChem (CID)	5311236
DrugBank	DB06826 N
ChemSpider	4470755 N
UNII	6X4F561V3W N
KEGG	D08661 Y
ChEMBL	CHEMBL1201407 N
ECHA InfoCard	100.227.145
Chemical and physical data
Formula	C22H38O5
Molar mass	382.534 g/mol
3D model (Jmol)	Interactive image
SMILES O=C(O)CCC/C=C\C[C@H]1[C@@H](O)C[C@@H](O)[C@@H]1CCC(=O)CCCCCCC
InChI InChI=1S/C22H38O5/c1-2-3-4-5-8-11-17(23)14-15-19-18(20(24)16-21(19)25)12-9-6-7-10-13-22(26)27/h6,9,18-21,24-25H,2-5,7-8,10-16H2,1H3,(H,26,27)/b9-6-/t18-,19-,20+,21-/m1/s1 N Key:TVHAZVBUYQMHBC-SNHXEXRGSA-N N
NY (what is this?)  (verify)

Unoprostone (INN) is a prostaglandin analogue. Its isopropyl ester, unoprostone isopropyl, was marketed under the trade name Rescula for the management of open-angle glaucoma and ocular hypertension, but is now discontinued in the US.