Tropic acid

From Wikipedia, the free encyclopedia
Jump to: navigation, search
Tropic acid
Tropic acid.png
Names
IUPAC name
3-Hydroxy-2-phenylpropanoic acid
Other names
2-Phenylhydracrylic acid; Tropate
Identifiers
529-64-6 YesY
ChEBI CHEBI:CHEBI:30765 N
ChemSpider 10274 N
EC Number 209-020-6
Jmol 3D model Interactive image
KEGG C01456 N
MeSH C011377
PubChem 10726
Properties
C9H10O3
Molar mass 166.18 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is YesYN ?)
Infobox references

Tropic acid is a chemical with IUPAC name 3-hydroxy-2-phenylpropanoic acid and condensed structural formula HOCH2CHPhCOOH. It is a laboratory reagent used in the chemical synthesis of atropine and hyoscyamine. Tropic acid is a chiral substance, existing as either a racemic mixture or as a single enantiomer.

Synthesis[edit]

Tropic acid synthesis 1:[1] Tropic acid synthesis 2:[1]
Tropicacidsynthesis1.svg
Tropic acid synthesis 2.svg

Prepn:[2][3][4]

References[edit]

  1. ^ a b Gadzikowska, M; Grynkiewicz, G (2002). "Tropane alkaloids in pharmaceutical and phytochemical analysis". Acta poloniae pharmaceutica. 59 (2): 149–60. PMID 12365608. 
  2. ^ Sletzinger, Paulsen, U.S. Patent 2,390,278 (1945 to Merck & Co.).
  3. ^ Blicke, U.S. Patent 2,716,650 (1955 to University of Michigan).
  4. ^ DE 923426  (1955 to Sterling Drug).