L-694247

L-694247

Names
IUPAC name (2-[5-[3-(4-methylsulphonylamino)benzyl-1,2,4-oxadiazol-5-yl]-1H-indole-3-yl]ethylamine)
Identifiers
3D model (Jmol)	Interactive image
ChEBI	CHEBI:92341
ChemSpider	116658
PubChem CID	132059
InChI InChI=1S/C20H21N5O3S/c1-29(26,27)25-16-5-2-13(3-6-16)10-19-23-20(28-24-19)14-4-7-18-17(11-14)15(8-9-21)12-22-18/h2-7,11-12,22,25H,8-10,21H2,1H3 Key: HKXMQLISPYELRD-UHFFFAOYSA-N
SMILES CS(=O)(=O)Nc1ccc(cc1)Cc2nc(on2)c3ccc4c(c3)c(c[nH]4)CCN
Properties
Chemical formula	C20H21N5O3S
Molar mass	411.48 g mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

L-694247 is a somewhat selective 5-HT_1D agonist, with a 10-fold greater affinity for the 5-HT_1B receptor, and 25-fold greater affinity for the 5-HT_1A receptor. When L-694247 was injected intraventricularly in dehydrated rats, it inhibited water intake. Pre-treatment with a 5-HT_1D antagonist abolished this effect. Administration of L-694,247 to normally hydrated rats had no effect on water intake.