Etanautine
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Clinical data | |
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ATC code | N04AB01 (WHO) |
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CAS Number | 857401-00-4 |
ChemSpider | 8430627 |
Chemical and physical data | |
Formula | C26H31N5O5 |
Molar mass | 493.555 g/mol |
3D model (Jmol) | Interactive image |
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Etanautine, also known as diphenhydramine monoacefyllinate, is an anticholinergic used as an antiparkinsonian agent. It is a 1:1 salt of diphenhydramine with acefylline, similar to the diphenhydramine/8-chlorotheophylline combination product dimenhydrinate.
As with dimenhydrinate, the stimulant effect of the acefylline counteracts the sedative effect from the diphenhydramine, resulting in an improved therapeutic profile.
The 1:2 salt diphenhydramine diacefylline (with two molecules of acefylline to each molecule of diphenhydramine) is also used in medicine, under the brand name Nautamine.
References[edit]
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