6-Chloro-5-ethoxy-N-(pyridin-2-yl)indoline-1-carboxamide

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6-Chloro-5-ethoxy-N-(pyridin-2-yl)indoline-1-carboxamide
CEPC structure.png
Identifiers
Chemical and physical data
Formula C16H16ClN3O2
Molar mass 317.769 g/mol
3D model (Jmol)

6-Chloro-5-ethoxy-N-(pyridin-2-yl)indoline-1-carboxamide (CEPC) is a drug which acts as a potent and selective antagonist for the serotonin 5-HT2C receptor. In animal studies it was found to potentiate the conditioned place preference induced by low-dose amphetamine, demonstrating that 5-HT2C-mediated disinhibition of dopamine release can cause interactions with dopaminergic drugs.[1]

See also[edit]

References[edit]

  1. ^ McCorvy JD, Harland AA, Maglathlin R, Nichols DE. A 5-HT(2C) receptor antagonist potentiates a low dose amphetamine-induced conditioned place preference. Neuroscience Letters. 2011 Nov 7;505(1):10-3. PMID 21827831
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