6-CAT

6-CAT
Clinical data
Routes of; administration	Oral
Legal status
Legal status	Uncontrolled;
Identifiers
	IUPAC name 6-Chloro-1,2,3,4-tetrahydronaphtalen-2-amine;
PubChem (CID)	16244336
ChemSpider	11269876
Chemical and physical data
3D model (Jmol)	Interactive image
	SMILES C1CC2=C(CC1N)C=CC(=C2)Cl ;
	InChI InChI=1S/C10H12ClN/c11-9-3-1-8-6-10(12)4-2-7(8)5-9/h1,3,5,10H,2,4,6,12H2 ; Key:CJRJTCMSQLEPFQ-UHFFFAOYSA-N ;
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6-Chloro-2-aminotetralin (6-CAT) is a drug which acts as a selective serotonin releasing agent (SSRA) and is a putative entactogen in humans.^[1]^[2] It is a rigid analogue of para-chloroamphetamine (PCA).^[1]

According to Nichols et al.,^[3] 6-CAT is a non-neurotoxic analog of PCA.

References[edit]

^ ^a ^b Fuller RW; Perry KW; Baker JC; Molloy BB (November 1974). "6-Chloro-2-aminotetralin, a rigid Conformational analog of 4-chloroamphetamine: pharmacologic properties of it and related compounds in rats". Archives Internationales de Pharmacodynamie et de Thérapie. 212 (1): 141–53. PMID 4455127.
^ Fuller, RW; Wong, DT; Snoddy, HD; Bymaster, FP (1977). "Comparison of the effects of 6-chloro-2-aminotetralin and of ORG 6582, a related chloroamphetamine analog, on brain serotonin metabolism in rats". Biochem. Pharmacol. 26 (1): 1,333–1,337.
^ Johnson, M. P.; Frescas, S. P.; Oberlender, R.; Nichols, D. E. (1991). "Synthesis and pharmacological examination of 1-(3-methoxy-4-methylphenyl)-2-aminopropane and 5-methoxy-6-methyl-2-aminoindan: Similarities to 3,4-(methylenedioxy)methamphetamine (MDMA)". Journal of Medicinal Chemistry. 34 (5): 1662–1668. doi:10.1021/jm00109a020. PMID 1674539.

v t e Empathogens/entactogens (category)

Phenylalkyl- amines (other than cathinones)	Unfused benzene ring: 4-CAB 4-FA 4-FMA 4-MTA 4,4'-DMAR Ariadne Metaescaline MMA PMA PMEA PMMA Benzodioxine: EDMA Benzodioxoles: Phenethylamine: { Lophophine } Amphetamines: { 2-Methyl-MDA 2,3-MDA 3,4-MDA 5-Methyl-MDA 6-Methyl-MDA DiFMDA DMMDA DMMDA-2 EIDA MDEA MDMA MDMOH MDOH MMDA MMDA-2 MMDMA } 1-Phenylbutan-2-amines: { BDB EBDB MBDB } Phentermines: { MDMP MDPH } Benzofurans and dihidrobenzofurans: 5-APB 5-APDB 5-EAPB 5-MAPB 5-MAPDB 5-MBPB 6-APB 6-APDB 6-EAPB 6-MAPB 6-MAPDB Indanes: 5-APDI 5-MAPDI Indole: 6-API Naphtalenes: Methamnetamine Naphthylaminopropane Tetralin: 6-APT

Cyclized phenyl- alkylamines	Aminoindanes: 5-IAI AMMI ETAI MDAI MDMAI MMAI NM-2-AI TAI Aminotetralins: 6-CAT MDAT MDMAT

Cathinones	3-MMC 4-EMC Brephedrone Butylone Ethylone Eutylone Flephedrone Mephedrone Methedrone Methylone Pentylone

Tryptamines	4-Methyl-αET αET αMT

Chemical classes	Substituted amphetamine Sub. benzofuran Sub. cathinone Sub. MDPEA Sub. PEA Sub. tryptamine

Clinical data

Routes of administration	Oral
Legal status
Legal status	Uncontrolled
Identifiers
IUPAC name 6-Chloro-1,2,3,4-tetrahydronaphtalen-2-amine
PubChem (CID)	16244336
ChemSpider	11269876^Y
Chemical and physical data
3D model (Jmol)	Interactive image
SMILES C1CC2=C(CC1N)C=CC(=C2)Cl
InChI InChI=1S/C10H12ClN/c11-9-3-1-8-6-10(12)4-2-7(8)5-9/h1,3,5,10H,2,4,6,12H2^Y Key:CJRJTCMSQLEPFQ-UHFFFAOYSA-N^Y
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