Arbaclofen placarbil
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| ATC code | none |
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| CAS Number | 847353-30-4 |
| PubChem (CID) | 11281011 |
| ChemSpider | 9456008 |
| KEGG | D08861  Y |
| ChEMBL | CHEMBL2107312 Y |
| ECHA InfoCard | 100.221.150 |
| Chemical and physical data | |
| Formula | C19H26ClNO6 |
| Molar mass | 399.86 g/mol |
| 3D model (Jmol) | Interactive image |
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Arbaclofen placarbil (ar-BAC-loe-fen pla-KAR-bil, also known as XP19986) is a prodrug of R-baclofen. Arbaclofen placarbil possesses more favorable pharmacokinetic profile than baclofen, with less fluctuations in plasma drug levels. It was being developed as a potential treatment for patients with GERD and spasticity due to multiple sclerosis; however, in May 2013 XenoPort announced the termination of development because of unsuccessful results in phase III clinical trials.[1]
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Skeletal muscle relaxants (M03)
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