Quifenadine
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Not to be confused with quinidine.
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Clinical data | |
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Trade names | Fencarol |
Routes of administration |
Oral (tablets), IM injection |
ATC code | R06AX31 (WHO) |
Legal status | |
Legal status | |
Pharmacokinetic data | |
Bioavailability | 45% (Tmax = 1 hour)[1] |
Metabolism | Liver |
Identifiers | |
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Synonyms | 3-Quinuclidinyldiphenylmethanol |
CAS Number | 10447-38-8 |
PubChem (CID) | 65600 |
ChemSpider | 59041 |
UNII | W9A18RJ49B ![]() |
KEGG | D10230 |
ChEMBL | CHEMBL1187694 |
Chemical and physical data | |
Formula | C20H23NO |
Molar mass | 293.40 g/mol |
3D model (Jmol) | Interactive image |
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Quifenadine (Russian: хифенадин, trade name: Phencarol, Фенкарол) is an 2nd generation antihistamine drug, marketed mainly in post-Soviet countries.[2][3] Chemically, it is a quinuclidine derivative.
Indications[edit]
- Allergic rhinitis
- Acute and chronic urticaria
- Angioedema
- Dermatitis
- Atopic dermatitis
- Pruritus[1]
References[edit]
- ^ a b "Fencarol (quifenadine) Tablets, for Oral Use. Full Prescribing Information". State Register of Medicines (in Russian). Retrieved 4 January 2016.
- ^ "Quifenadine". Drugs.com. Retrieved 28 January 2014.
- ^ Makarov, L.; Balykova, L.; Soldatova, O.; Komolyatova, V.; Serebruany, V. (2010). "The antiarrhythmic properties of quifenadine, H1-histamine receptor blocker in children with premature beats: A randomized controlled pilot trial". American journal of therapeutics. 17 (4): 396–401. doi:10.1097/MJT.0b013e3181a86987. PMID 19487925.
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