Cyanopindolol

Cyanopindolol
Clinical data
ATC code	none
Identifiers
	IUPAC name (RS)-4-[3-(tert-Butylamino)-2-hydroxypropoxy]-1H-indole-2-carbonitrile;
CAS Number	69906-85-0
PubChem (CID)	155346
IUPHAR/BPS	132
ChemSpider	136847
ChEMBL	CHEMBL378501
Chemical and physical data
Formula	C16H21N3O2
Molar mass	287.36 g/mol
3D model (Jmol)	Interactive image
Chirality	Racemic mixture
	SMILES N#CC1=CC2=C(OCC(CNC(C)(C)C)O)C=CC=C2N1 ;
	InChI InChI=1S/C16H21N3O2/c1-16(2,3)18-9-12(20)10-21-15-6-4-5-14-13(15)7-11(8-17)19-14/h4-7,12,18-20H,9-10H2,1-3H3 ; Key:QXIUMMLTJVHILT-UHFFFAOYSA-N ;
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Cyanopindolol is a drug related to pindolol which acts as both a β₁ adrenoceptor antagonist and a 5-HT_1A receptor antagonist. Its radiolabelled derivative iodocyanopindolol has been widely used in mapping the distribution of beta adrenoreceptors in the body.^[1]

References[edit]

^ Hoyer, D.; Engel, G. (1983). "Binding of 125I-cyanopindolol to beta-1-adrenoceptors in a high and low affinity state". Journal of Receptor Research. 3 (1-2): 45–59.

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v t e Beta blockers (C07)

β, non-selective	Alprenolol Bopindolol Bupranolol Carteolol Cloranolol Mepindolol Nadolol Oxprenolol Penbutolol Pindolol/Iodopindolol Propranolol Sotalol Tertatolol Timolol

β₁-selective	Acebutolol Atenolol Betaxolol Bevantolol Bisoprolol Celiprolol Epanolol Esmolol Landiolol Metoprolol Nebivolol Practolol S-Atenolol Talinolol

β₂-selective	Butaxamine

α₁- + β-selective	Arotinolol Carvedilol Labetalol

^#WHO-EM ^‡Withdrawn from market Clinical trials: ^†Phase III ^§Never to phase III