6β-Naltrexol-d4
From Wikipedia, the free encyclopedia
 |
|
| Systematic (IUPAC) name | |
|---|---|
|
(1S,5R,13R,14R,17S)-4-(cyclopropylmethyl)(13,14,15,15-²H₄)-12-oxa-4-azapentacyclo[9.6.1.0¹,¹³.0⁵,¹⁷.0⁷,¹⁸]octadeca-7(18),8,10-triene-10,14,17-triol
|
|
| Identifiers | |
| CAS Number | 1279034-32-0 |
| ATC code | None |
| PubChem | CID 46782432 |
| Chemical data | |
| Formula | C20H21D4NO4 |
| Molar mass | 347.45 g·mol−1 |
| 3D model (Jmol) | Interactive image |
|
|
|
|
6β-Naltrexol-d4, also known as 6β-hydroxynaltrexone-d4, is a deuterium-labeled form of 6β-Naltrexol used for NMR imaging. Unlike opioid inverse agonists such as naloxone and naltrexone (which are often dubbed "antagonists" for simplicity's sake), 6β-naltrexol and 6β-naltrexol-d4 are opioid neutral antagonists.[1]
References[edit]
- ^ The Relative Potency of Inverse Opioid Agonists and a Neutral Opioid Antagonist in Precipitated Withdrawal and Antagonism of Analgesia and Toxicity. Sunil Sirohi, Shveta V. Dighe, Priyanka A. Madia and Byron C. Yoburn
 |
This drug article relating to the nervous system is a stub. You can help Wikipedia by expanding it. |
