Lazabemide

From Wikipedia, the free encyclopedia
Jump to: navigation, search
Lazabemide
Lazabemide.svg
Clinical data
Routes of
administration
Oral
ATC code none
Legal status
Legal status
  • Development terminated
Identifiers
CAS Number 103878-84-8
PubChem (CID) 71307
IUPHAR/BPS 6640
ChemSpider 64426
UNII 420HD787N9 YesY
KEGG D04681
Chemical and physical data
Formula C8H10ClN3O
Molar mass 199.64 g/mol

Lazabemide (proposed trade names Pakio, Tempium) is a reversible and selective inhibitor of monoamine oxidase B (MAO-B) that was under development as an antiparkinsonian agent but was never marketed.[1]

References[edit]

  1. ^ Henriot S, Kuhn C, Kettler R, Da Prada M (1994). "Lazabemide (Ro 19-6327), a reversible and highly sensitive MAO-B inhibitor: preclinical and clinical findings.". J Neural Transm Suppl. 41: 321–325. PMID 7931245.