Evoxine

Evoxine
Names
	IUPAC name (±)-1-(4,8-Dimethoxyfuro[2,3-b]quinolin-7-yl)oxy-3-methylbutane-2,3-diol
	Other names Haploperine
Identifiers
CAS Number	522-11-2
3D model (Jmol)	Interactive image
ChEMBL	ChEMBL1416006
ChemSpider	66130
PubChem	73416
	InChI InChI=1S/C18H21NO6/c1-18(2,21)13(20)9-25-12-6-5-10-14(16(12)23-4)19-17-11(7-8-24-17)15(10)22-3/h5-8,13,20-21H,9H2,1-4H3 Key: FGANMDNHTVJAHL-UHFFFAOYSA-N ; InChI=1/C18H21NO6/c1-18(2,21)13(20)9-25-12-6-5-10-14(16(12)23-4)19-17-11(7-8-24-17)15(10)22-3/h5-8,13,20-21H,9H2,1-4H3 Key: FGANMDNHTVJAHL-UHFFFAOYAV ;
	SMILES CC(C)(C(COC1=C(C2=C(C=C1)C(=C3C=COC3=N2)OC)OC)O)O ;
Properties
Chemical formula	C18H21NO6
Molar mass	347.37 g·mol−1
Pharmacology
ATC code	none
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
	verify (what is ?)
	Infobox references

Evoxine (haploperine) is a furoquinoline alkaloid with hypnotic and sedative effects. It is found naturally in a variety of Australian and African plants including Evodia xanthoxyloides^[1] and Teclea gerrardii.^[2]

References[edit]

^ Eastwood, FW; Hughes, GK; Ritchie, E. (1954). "Alkaloids of the Australian Rutaceae: Evodia xanthoxyloides F.Muell. IV. The structures of Evoxine and Evoxoidine". Australian Journal of Chemistry. 7 (1): 87–98. doi:10.1071/CH9540087.
^ Waffo, AF; Coombes, PH; Crouch, NR; Mulholland, DA; El Amin, SM; Smith, PJ (2007). "Acridone and furoquinoline alkaloids from Teclea gerrardii (Rutaceae: Toddalioideae) of southern Africa.". Phytochemistry. 68 (5): 663–7. doi:10.1016/j.phytochem.2006.10.011. PMID 17174364.

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