Cytidine triphosphate
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| Names | |
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| IUPAC name
[(2R,3S,4R,5R)-5-(4-amino-2-oxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl(hydroxy-phosphonooxyphosphoryl)hydrogen phosphate
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| Other names
CTP; Cytidine-5'-triphosphate; Cytidine 5'-(tetrahydrogen triphosphate)
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| Identifiers | |
65-47-4  |
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| 3D model (Jmol) | Interactive image Interactive image |
| ChemSpider | 19952488 |
| ECHA InfoCard | 100.000.556 |
| 1741 | |
| MeSH | Cytidine+triphosphate |
| PubChem | 6176 |
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| Properties | |
| C9H16N3O14P3 | |
| Molar mass | 483.156 |
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Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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| Infobox references | |
Cytidine triphosphate is a pyrimidine nucleoside triphosphate.
CTP, much like ATP, consists of a ribose sugar, and three phosphate groups. The major difference between the two molecules is the base used, which in CTP is cytosine.
CTP is a substrate in the synthesis of RNA.
CTP is a high-energy molecule similar to ATP, but its role as an energy coupler is limited to a much smaller subset of metabolic reactions. CTP is a coenzyme in metabolic reactions like the synthesis of glycerophospholipids and glycosylation of proteins.
CTP acts as an inhibitor of the enzyme Aspartate carbamoyltransferase, which is used in pyrimidine biosynthesis.[1]
See also[edit]
References[edit]
- ^ Blackburn, G. Michael. Nucleic Acids in Chemistry and Biology. The Royal Society of Chemistry, 2006, p. 119-120.
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