Trapidil
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Clinical data | |
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Trade names | Rocornal, Avantrin, Travisco |
AHFS/Drugs.com | International Drug Names |
Routes of administration |
By mouth |
ATC code | C01DX11 (WHO) |
Legal status | |
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Identifiers | |
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CAS Number | 15421-84-8 |
PubChem (CID) | 5531 |
ChemSpider | 5330 |
UNII | EYG5Y6355E |
ECHA InfoCard | 100.035.834 |
Chemical and physical data | |
Formula | C10H15N5 |
Molar mass | 205.26 g/mol |
3D model (Jmol) | Interactive image |
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Trapidil is a vasodilator and an antiplatelet drug.[1][2] It also acts as an antagonist of platelet-derived growth factor.[3]
References[edit]
- ^ Büyükafşar, K; Yazar, A; Düşmez, D; Oztürk, H; Polat, G; Levent, A (October 2001). "Effect of Trapidil, an Antiplatelet and Vasodilator Agent on Gentamicin-Induced Nephrotoxicity in Rats". Pharmacological Research. 44 (4): 321–8. doi:10.1006/phrs.2001.0864. PMID 11592868.
- ^ Liu, M; Sun, Q; Wang, Q; Wang, X; Lin, P; Yang, M; Yan, Y (March–April 2014). "Effect of Trapidil in Myocardial Ischemia-Reperfusion Injury in Rabbit". Indian Journal of Pharmacology. 46 (2): 207–10. doi:10.4103/0253-7613.129320. PMC 3987192. PMID 24741195.
- ^ Maresta, A; Balducelli, M; Cantini, L; Casari, A; Chioin, R; Fabbri, M; Fontanelli, A; Monici Preti, PA; Repetto, S; De Servi, S (December 1994). "Trapidil (triazolopyrimidine), a Platelet-Derived Growth Factor Antagonist, Reduces Restenosis After Percutaneous Transluminal Coronary Angioplasty. Results of the Randomized, Double-Blind STARC Study". Circulation. 90 (6): 2710–5. PMID 7994812.
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