SIB-1553A
From Wikipedia, the free encyclopedia
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| Names | |
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| IUPAC name
(R/S)-4-{[2-(1-Methyl-2-pyrrolidinyl)ethyl]thio}phenol hydrochloride
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| Identifiers | |
191611-76-4  |
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| 3D model (Jmol) | Interactive image |
| ChEMBL | ChEMBL47850 |
| ChemSpider | 4470512 |
| PubChem | 5310968 |
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| Properties | |
| C13H19NOS | |
| Molar mass | 237.36 g·mol−1 |
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Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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| Infobox references | |
SIB-1553A is a nicotinic acetylcholine receptor agonist that is selective for receptors with a β4 subunit. Administration of SIB-1553A improved memory and attention in a Parkinson's disease model.[1]
References[edit]
- ^ Schneider, JS (July 2003). "The Subtype-Selective Nicotinic Acetylcholine Receptor Agonist SIB-1553A Improves Both Attention and Memory Components of a Spatial Working Memory Task in Chronic Low Dose 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine-Treated Monkeys". Journal of Pharmacology and Experimental Therapeutics. 306 (1): 401–6. doi:10.1124/jpet.103.051912. PMID 12721323.
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