Furazabol

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Furazabol
Skeletal formula of furazabol
Space-filling model of the furazabol molecule
Clinical data
Routes of
administration
Oral
ATC code B
Legal status
Legal status
Pharmacokinetic data
Biological half-life 4 hours
Excretion Urinary
Identifiers
Synonyms 17α-methyl-5α-androsta-2,3-furazan-17β-ol
CAS Number 1239-29-8 YesY
PubChem (CID) 14708
DrugBank DB01514 YesY
ChemSpider 14032 YesY
UNII 2W07HSP5PX YesY
ChEMBL CHEMBL1893554 N
ECHA InfoCard 100.013.621
Chemical and physical data
Formula C20H30N2O2
Molar mass 330.4694
3D model (Jmol) Interactive image
 NYesY (what is this?)  (verify)

Furazabol (brand names Frazalon, Miotolan), also known as androfurazanol, is an analogue of the anabolic steroid stanozolol. It differs from stanozolol by having a furazan ring system in place of the pyrazole.[1] It has a c-17alpha methyl group, which allows it to be taken orally and causes hepatotoxicity in some individuals.[citation needed]

According to William Llewellyn, author of Anabolics 2007, the cholesterol-lowering effects of furazabol are a myth. In the 1970s, research studies showed that furazabol along with many other orally-active AAS like Anavar (oxandrolone) lowered total serum cholesterol.[citation needed] It was subsequently established that the cholesterol reduction from oral AAS was the result of suppressed HDL levels. As such, it would be expected that furazabol, like other oral anabolic steroids, while reducing total cholesterol levels would still adversely affect the HDL/LDL ratio and increase the risk of cardiovascular disease.[citation needed]

The Canadian sprinter Ben Johnson tested positive for stanozolol after winning the gold medal in the 100 meter sprint at the 1988 Summer Olympics.[citation needed] His doctor, Jamie Astaphan, maintains that his urine sample was sabotaged because Johnson was administered furazabol, which was not an IOC banned substance at the time.[citation needed] Subsequently, training partner and fellow Charlie Francis athlete Angela Issajenko (Taylor), in her book "Running Risks" outlined a theory stating Ben Johnson actually was using stanozolol. She substantiated this by stating that her supply of what she thought was furazabol was retested following the Dubin Inquiry and was found to be stanozolol, explaining the positive test.[citation needed]

References[edit]

  1. ^ US 3245988, "Steroid [2, 3-c] furazan compounds and the process for the production thereof"