5-EAPB
![]() |
|
![]() |
|
Clinical data | |
---|---|
Pregnancy category |
|
ATC code |
|
Identifiers | |
|
|
CAS Number | |
ChemSpider | |
UNII | |
Chemical and physical data | |
Formula | C13H17NO |
Molar mass | 203.28 g/mol (freebase) 239.78 g/mol (hydrochloride) |
3D model (Jmol) | |
|
|
|
5-EAPB (1-(benzofuran-5-yl)-N-ethylpropan-2-amine) is an entactogenic amphetamine which is structurally related to 5-MAPB and 5-APB. It might be predicted to show similar effects to these drugs in humans, but the pharmacology of 5-EAPB remains unstudied as of 2013.
5-EAPB is similar in structure to compounds such as 5-APB which are claimed to be agonists of the 5-HT2C receptor [1] as well as a triple monoamine reuptake inhibitors, however 5-EAPB is not listed as an example in this patent, and it is not yet established to what extent the activity of 5-EAPB resembles that of 5-APB.
Legality[edit]
As an N-ethyl derivative of 5-APB, 5-EAPB falls outside the scope of the Temporary Class Drug ban issued by the Home Office on June 10, 2013,[2] and remains uncontrolled in the UK as of November 2013. The ACMD has advised that 5-EAPB (and other -APBs) are moved to Class B,[3] this will likely come into action on 10 June 2014.
5-EAPB is listed in the Fifth Schedule of the Misuse of Drugs Act (MDA) and therefore illegal in Singapore as of May 2015.[4]
Adverse reactions and deaths[edit]
Three people in their 30s were hospitalised after each taking approximately 500 mg of 5-EAPB, one of whom later died in hospital, whilst attending Brownstock music festival in Essex, UK on August 31, 2013.[5][6]
References[edit]
- ^ US patent 7045545, Karin Briner et al, "Aminoalkylbenzofurans as serotonin (5-HT(2c)) agonists", published 2000-01-19, issued 2006-16-03
- ^ "Temporary class drug order report on 5-6APB and NBOMe compounds". UK Home Office. 4 Jun 2013. Retrieved 2013-07-10.
- ^ https://www.gov.uk/government/news/acmd-recommends-permanent-ban-on-two-legal-highs
- ^ "CNB NEWS RELEASE". Central Narcotics Bureau (CNB). 30 April 2015. Retrieved 24 July 2015.
- ^ Festivalgoer's death prompts drug warning. The Guardian, 1 September 2013[1]
- ^ [2]
Phenylalkyl- amines (other than cathinones) |
|
---|---|
Cyclized phenyl- alkylamines |
|
Cathinones | |
Tryptamines | |
Chemical classes |
Phenethylamines |
|
---|---|
Amphetamines |
|
Phentermines |
|
Cathinones |
|
Phenylisobutylamines | |
Phenylalkylpyrrolidines | |
Catecholamines (and close relatives) |
|
Miscellaneous |
|