Thiorphan
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Systematic (IUPAC) name | |
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(±)-2-[(2-benzyl-3-sulfanyl-propanoyl)amino]acetic acid
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Identifiers | |
CAS Number | 76721-89-6 N |
PubChem | CID 3132 |
DrugBank | DB08626 N |
ChemSpider | 3020 Y |
UNII | B79L7B5X3Z N |
ChEMBL | CHEMBL10247 Y |
Chemical data | |
Formula | C12H15NO3S |
Molar mass | 253.32 g/mol |
Chirality | Racemic mixture |
3D model (Jmol) | Interactive image |
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NY (what is this?) (verify) |
Thiorphan is the active metabolite of the antidiarrheal racecadotril (acetorphan).[1] It prevents the degradation of endogenous enkephalins by acting as an enkephalinase inhibitor.[1]
See also[edit]
References[edit]
- ^ a b Spillantini MG, Geppetti P, Fanciullacci M, Michelacci S, Lecomte JM, Sicuteri F (June 1986). "In vivo 'enkephalinase' inhibition by acetorphan in human plasma and CSF". European Journal of Pharmacology. 125 (1): 147–50. doi:10.1016/0014-2999(86)90094-4. PMID 3015640.
Rehydration | |
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Intestinal anti-infectives | |
Intestinal adsorbents | |
Antipropulsives (opioids) |
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Intestinal anti-inflammatory agents |
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Antidiarrheal micro-organisms | |
Other antidiarrheals |
This drug article relating to the gastrointestinal system is a stub. You can help Wikipedia by expanding it. |
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