Thiethylperazine
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Clinical data | |
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AHFS/Drugs.com | Micromedex Detailed Consumer Information |
ATC code | R06AD03 (WHO) |
Pharmacokinetic data | |
Protein binding | 60% |
Identifiers | |
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CAS Number | 1420-55-9 ![]() |
PubChem (CID) | 5440 |
IUPHAR/BPS | 7306 |
DrugBank | DB00372 ![]() |
ChemSpider | 5245 ![]() |
UNII | 8ETK1WAF6R ![]() |
KEGG | D02354 ![]() |
ChEBI | CHEBI:9544 ![]() |
ChEMBL | CHEMBL1378 ![]() |
ECHA InfoCard | 100.014.381 |
Chemical and physical data | |
Formula | C22H29N3S2 |
Molar mass | 399.618 g/mol |
3D model (Jmol) | Interactive image |
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Thiethylperazine (Torecan) is an antiemetic of the phenothiazine class. Though it was never licensed or used as an antipsychotic, it may have such effects.
Thiethylperazine activates the transport protein ABCC1 that clears beta-amyloid from brains of mice.[1]
References[edit]
- ^ Science Daily (September 1, 2011). "Alzheimer Disease: Transport Protein ABCC1 Plays Key Role in Clearing Beta-Amyloid from Brains of Mice.". Retrieved September 1, 2011.
Aminoalkyl ethers |
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Substituted alkylamines | |
Substituted ethylenediamines |
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Phenothiazine derivatives | |
Piperazine derivatives | |
Others for systemic use |
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For topical use |
Simple piperazines (no additional rings) |
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Phenylpiperazines |
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Benzylpiperazines | |
Diphenylalkylpiperazines (benzhydrylalkylpiperazines) |
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Pyrimidinylpiperazines | |
Pyridinylpiperazines | |
Benzo(iso)thiazolylpiperazines | |
Tricyclics (piperazine attached via side chain) |
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Others/Uncategorized |
Classes | |
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Antidepressants (TCAs and TeCAs) |
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Antihistamines |
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Antipsychotics |
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Anticonvulsants | |
Others |
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