Bromperidol

Bromperidol

Clinical data
Trade names	Bromidol, Bromodol
AHFS/Drugs.com	International Drug Names
Routes of administration	Oral
ATC code	N05AD06 (WHO)
Identifiers
IUPAC name 4-[4-(4-bromophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one
CAS Number	10457-90-6 N
PubChem (CID)	2448
ChemSpider	2354 Y
UNII	LYH6F7I22E Y
KEGG	D01101 Y
ChEMBL	CHEMBL28218 Y
ECHA InfoCard	100.030.845
Chemical and physical data
Formula	C21H23BrFNO2
Molar mass	420.315 g/mol
3D model (Jmol)	Interactive image
SMILES Fc1ccc(cc1)C(=O)CCCN3CCC(O)(c2ccc(Br)cc2)CC3
InChI InChI=1S/C21H23BrFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 Y Key:RKLNONIVDFXQRX-UHFFFAOYSA-N Y
NY (what is this?)  (verify)

Bromperidol (marketed as Bromidol, Bromodol) is a butyrophenone derivative. It is a potent and long-acting neuroleptic, used as an antipsychotic in the treatment of schizophrenia. It was discovered at Janssen Pharmaceutica in 1966.

References

• Poldinger W, Bures E, Haage H, Clinical study with bromperidol, a new butyrophenone derivative, Int Pharmacopsychiatry. 1977;12(1):20-4.
• Dubinsky B, McGuire JL, Niemegeers CJ, Janssen PA, Weintraub HS, McKenzie BE, Bromperidol, a new butyrophenone neuroleptic: a review, Psychopharmacology (Berl). 1982;78(1):1-7.