SDB-005

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SDB-005
SDB-005 structure.png
Legal status
Legal status
Identifiers
ChemSpider 30922481
Chemical and physical data
Systematic (IUPAC) name: naphthalen-1-yl 1-pentyl-1H-indazole-3-carboxylate
3D model (Jmol) Interactive image
Formula C23H22N2O2
Molar mass 358.17 g/mol

SDB-005 is an indazole-based synthetic cannabinoid that has been sold online as a designer drug.[1] It is presumed to be an agonist of the CB1 and CB2 cannabinoid receptors. SDB-005 is the indazole core analogue of PB-22 where the 8-hydroxyquinoline has also been replaced with a naphthalene group.

The code number SDB-005 was originally used for a different compound, the N-phenyl instead of N-benzyl analogue of SDB-006. This compound is a potent agonist of the CB1 receptor (Ki = 21 nM) and CB2 receptor (Ki = 140 nM).[2]

Original, non designer drug SDB-005

However SDB-005 was subsequently used as the name for the indazole-3-carboxylate compound mentioned above when it was sold in Europe as a designer drug, and was entered into the EMCDDA synthetic drug database under this name.[3] Consequently, there are now two distinct, yet fairly closely related cannabinoid compounds, which may both be referred to under the code SDB-005.

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