Benzobarbital
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| Systematic (IUPAC) name | |
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1-benzoyl-5-ethyl-5-phenyl-1,3-diazinane-2,4,6-trione
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| Identifiers | |
| CAS Number | 744-80-9  |
| ATC code | none |
| PubChem | CID 12938 |
| ChemSpider | 12402 |
| UNII | YNJ78BD0AH |
| ChEMBL | CHEMBL1338506  |
| Synonyms | Benzonal |
| Chemical data | |
| Formula | C19H16N2O4 |
| Molar mass | 336.341 g/mol |
| 3D model (Jmol) | Interactive image |
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Benzobarbital (Benzonal) is a barbiturate derivative. It has anticonvulsant effects and has been used for the treatment of epilepsy. [1]
It has similar liver enzyme inducing effects to the closely related drug phenobarbital, which may be exploited in some clinical applications. [2] [3]
References[edit]
- ^ Okudzhava, V. M.; Chankvetadze, B. G. (1989). "Pharmacological characteristics of an anti-convulsive drug Benzonal and the evaluation of its therapeutic effectiveness (literature review)". Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (in Russian). Moscow. 89 (11): 136–145. ISSN 0044-4588. PMID 2696306.
- ^ Nadzhimutdinov, K. N.; Khakimov, Z. Z.; Kabulov, Sh. M. (1992). "The advantages of benzonal as an inducer of the liver mono-oxygenase enzyme system compared to phenobarbital". Eksperimental'naia i klinicheskaia farmakologiia (in Russian). Moscow. 55 (1): 68–71. ISSN 0869-2092. PMID 1305441.
- ^ Novozheeva, T. P.; Saratikov, A. S.; Grishanova, A. U.; Gutkina, N. I.; Akhmedzhanov, R. R.; Khatsenko, O. G.; Kozlovskaia, N. E. (1991). "Benzonal--a phenobarbital-type of inducer of the mono-oxygenase system". Biulleten' eksperimental'noi biologii i meditsiny (in Russian). Moscow. 111 (2): 163–165. ISSN 0365-9615. OCLC 613807502. PMID 1854958.
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