5-MeO-DiBF

From Wikipedia, the free encyclopedia
Jump to: navigation, search
5-MeO-DiBF
5-MeO-DiBF structure.png
CAS Number none
Chemical and physical data
Systematic (IUPAC) name: N-[2-(5-Methoxy-1-benzofuran-3-yl)ethyl]-N-(propan-2-yl)propan-2-amine
3D model (Jmol) Interactive image
Formula C17H25NO2
Molar mass 275.381 g/mol

5-MeO-DiBF is a psychedelic[1] that has been sold online as a designer drug and was first definitively identified in December 2015 by a forensic laboratory in Slovenia.[2] It is thought to act as an agonist for the 5-HT1A and 5-HT2 family of serotonin receptors. It is related in structure to the psychedelic tryptamine derivative 5-MeO-DiPT, but with the indole nitrogen replaced by oxygen, making 5-MeO-DiBF a benzofuran derivative. It is several times less potent as a serotonin agonist than 5-MeO-DiPT and with relatively more activity at 5-HT1A, but still shows strongest effects at the 5-HT2 family of receptors.[3][4]

References[edit]

  1. ^ John F. Casale; Patrick A. Hays. "The Characterization of 2-(5-Methoxy-1-benzofuran-3-yl)-N,N-dimethylethanamine (5-MeO-BFE) and Differentiation from its N-Ethyl Analog" (PDF). Microgram Journal. 9 (1): 39–45. 
  2. ^ European Monitoring Center for Drugs and Drug Addiction – Europol 2015 Annual Report on the implementation of Council Decision 2005/387/JHA
  3. ^ Zbigniew Tomaszewski; Michael P. Johnson; Xuemei Huang; David E. Nichols (May 1992). "Benzofuran bioisosteres of hallucinogenic tryptamines". Journal of Medicinal Chemistry. 35 (11): 2061–2064. doi:10.1021/jm00089a017. PMID 1534585. 
  4. ^ D.J. Mckenna; D.B. Repke; L. Lo; S.J. Peroutka (March 1990). "Differential interactions of indolealkylamines with 5-hydroxytryptamine receptor subtypes". Neuropharmacology. 29 (3): 193–198. doi:10.1016/0028-3908(90)90001-8. PMID 2139186. 
Retrieved from "https://en.wikipedia.org/w/index.php?title=5-MeO-DiBF&oldid=744772998"